Övningar för Friedreichs ataxi (FRDA) — hjärtövervakning FÖRST, balansträning, omaveloxolon-eran

Lynch 2021 + Milne 2018 + Pandolfo 2009 GeneReviews framework. Friedreich's ataxia (FRDA) is an autosomal-recessive mitochondrial disorder caused by GAA repeat expansion in the FXN gene encoding frataxin. Typical onset 5-15 years. The clinical picture: progressive cerebellar ataxia (gait, then trunk + limb + speech) + dysarthria + sensory loss + areflexia + hypertrophic cardiomyopathy (the LEADING cause of mortality — most patients die from cardiac complications, not from ataxia disability), diabetes ~30% lifetime, scoliosis ~70%. Treatment was supportive only until 2023 — omaveloxolone (Skyclarys) became the first FDA-approved disease-modifying therapy that activates Nrf2 antioxidant response and modestly slows progression. Exercise framework per Milne 2018 + Lynch 2021 + Friedreich's Ataxia Research Alliance (FARA) consensus: graduated aerobic + balance training + light progressive resistance reduces SARA ataxia score + improves QoL + functional capacity; AVOID cardiac strain + Valsalva + max-effort lifts (cardiomyopathy makes these high-risk). Balance training is the core intervention — vestibular + visual + somatosensory exercises in a safe environment with progressive challenge. Annual cardiology surveillance (echo + ECG + Holter) is non-negotiable — sudden death from arrhythmia is a real risk. Diabetes screening (fasting glucose + HbA1c annually).

Volya's catalogue carries the foundation moves: supported-glute-bridge for posterior chain (NOT failure-load — cardiac strain), scapular-retraction for posture (scoliosis-related compensatory), cat-cow for spinal mobility, supine-knee-to-chest for low-back release, diaphragmatic-breathing for parasympathetic + breath control (training to NOT Valsalva is a key FRDA skill given cardiomyopathy), single-leg-stance for balance core (the central FRDA intervention — graduated difficulty, safe environment, assisted as needed), tandem-stance for balance progression, sit-to-stand for functional + bone-loading within cardiac limits, ankle-pump for circulation. The AI coach also knows the nutrition side — cardiac-protective low-sodium <2 g/day + Mediterranean + omega-3 1-3 g/day + cardiology team, diabetes screening + low-glycaemic Mediterranean (30% lifetime), protein 1.2-1.4 g/kg, calcium 1000-1200 + vit D + weight-bearing within balance/cardiac limits, Coenzyme Q10 + idebenone modest benefit per Cooper 2008 + Hausse 2002 (coordinate with neuro/cardio), vit E adequate, vit B12 + folate, AVOID alcohol excess + AVOID smoking absolutely (CV + ataxia compound), dysphagia soft+moist + SLP if late-stage, scoliosis post-surgical fusion high-protein + vit C + zinc + Ca + vit D. CRITICAL: Friedreich's Ataxia Research Alliance (FARA) + MDA + Ataxia UK + neurology + cardiology (annual echo + ECG + Holter — survival lever) + endocrinology if diabetes + orthopedics if scoliosis + SLP if dysphagia + dietitian + PT (FRDA-experienced) + genetic counselling (autosomal recessive — sibling + reproductive considerations). This is NEVER a replacement for FARA-affiliated multidisciplinary care.